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Image Search Results
Journal: medRxiv
Article Title: Rapid antifouling nanocomposite coating enables highly sensitive multiplexed electrochemical detection of myocardial infarction and concussion markers
doi: 10.1101/2021.06.13.21258856
Figure Lengend Snippet: Schematic and Calibration curves for different biomarkers of Myocardial infarction and Traumatic Brain Injury using antifouling nanocomposite coated EC Biosensors and ELISA. a, Schematic for the preparation and assay steps for the EC Biosensor. b-g, Calibration curves for different biomarkers. Left y-axis shows current density for different concentrations of biomarkers run on EC biosensors (red circle) using unprocessed human plasma while right y-axis shows mean absorbance (a.u) for different concentration of biomarkers run in ELISA plate using plasma (black triangle). Different biomarkers tested include b, cardiac troponin I (cTnI); n=6, c, cardiac troponin ITC complex (cTnI-TC); n=5, d, B-type natriuretic peptide (BNP); n=4, e, N-terminal (NT)-pro hormone BNP (NT-proBNP); n=4, f, Glial fibrillary acidic protein (GFAP); n=3, and g, S100b protein; n=3. Error bars represent the s.d. of the mean; n=2 for all ELISA assay. Analysis was done using 4-Parameter Logistic (4PL) curve fitting. Lowest concentration showing significant difference against background (0 ng/mL) was determined by unpaired t -test ( ns P > 0 . 05; * P < 0.05; ** P < 0.01 *** P < 0.001; **** P < 0.0001; all two tailed.
Article Snippet: Detection antibody used include anti-cTnI (abcam, no. ab243982),
Techniques: Enzyme-linked Immunosorbent Assay, Concentration Assay, Two Tailed Test
Journal: medRxiv
Article Title: Rapid antifouling nanocomposite coating enables highly sensitive multiplexed electrochemical detection of myocardial infarction and concussion markers
doi: 10.1101/2021.06.13.21258856
Figure Lengend Snippet: Schematic and Calibration curves for different biomarkers of Myocardial infarction and Traumatic Brain Injury using antifouling nanocomposite coated EC Biosensors and ELISA. a, Schematic for the preparation and assay steps for the EC Biosensor. b-g, Calibration curves for different biomarkers. Left y-axis shows current density for different concentrations of biomarkers run on EC biosensors (red circle) using unprocessed human plasma while right y-axis shows mean absorbance (a.u) for different concentration of biomarkers run in ELISA plate using plasma (black triangle). Different biomarkers tested include b, cardiac troponin I (cTnI); n=6, c, cardiac troponin ITC complex (cTnI-TC); n=5, d, B-type natriuretic peptide (BNP); n=4, e, N-terminal (NT)-pro hormone BNP (NT-proBNP); n=4, f, Glial fibrillary acidic protein (GFAP); n=3, and g, S100b protein; n=3. Error bars represent the s.d. of the mean; n=2 for all ELISA assay. Analysis was done using 4-Parameter Logistic (4PL) curve fitting. Lowest concentration showing significant difference against background (0 ng/mL) was determined by unpaired t -test ( ns P > 0 . 05; * P < 0.05; ** P < 0.01 *** P < 0.001; **** P < 0.0001; all two tailed.
Article Snippet: Antigen includes [cTnI (Medix Biochemica, no. 610102),
Techniques: Enzyme-linked Immunosorbent Assay, Concentration Assay, Two Tailed Test